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Caspase-3 cleaves the formin-homology-domain-containing protein FHOD1 during apoptosis to generate a C-terminal fragment that is targeted to the nucleolus |
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| Authors: | Isabelle Ménard François G. Gervais Donald W. Nicholson Sophie Roy |
| Affiliation: | (1) Department of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec, Canada, H3G 1Y6;(2) Department of Biochemistry and Molecular Biology, Merck Frosst Centre for Therapeutic Research, 16711 TransCanada Hwy., Quebec, Canada, H9H 3L1;(3) Merck Research Laboratories – 126 E. Lincoln Ave., Rahway, NJ, 07065;(4) Cardiovascular Diseases, Merck Research Laboratories – 126 E., Lincoln Ave., Rahway, NJ, 07065 |
| Abstract: | |
| Keywords: | FHOD1 FHOS Nucleolus Nucleus Apoptosis Caspase Cleavage |
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