Antiviral reactivities of gammadelta T cells |
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Authors: | Poccia Fabrizio Agrati Chiara Martini Federico Capobianchi Maria Rosaria Wallace Marianne Malkovsky Miroslav |
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Affiliation: | Unit of Cellular Immunology, National Institute for Infectious Diseases Lazzaro Spallanzani - IRCCS, Via Portuense 292, 00149 Rome, Italy. poccia@inmi.it |
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Abstract: | The complex antiviral immune mechanisms involve both adaptive and innate reactions mediated by gammadelta T lymphocytes, whose unique immunosurveillance contributions are analyzed here in different clinical and experimental settings. It is beyond any doubt that the fast, potent, cytotoxic as well as non-cytolytic antiviral activities of gammadelta T cells are critical in protecting the host against diverse viral pathogens. |
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