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Antiviral reactivities of gammadelta T cells
Authors:Poccia Fabrizio  Agrati Chiara  Martini Federico  Capobianchi Maria Rosaria  Wallace Marianne  Malkovsky Miroslav
Affiliation:Unit of Cellular Immunology, National Institute for Infectious Diseases Lazzaro Spallanzani - IRCCS, Via Portuense 292, 00149 Rome, Italy. poccia@inmi.it
Abstract:The complex antiviral immune mechanisms involve both adaptive and innate reactions mediated by gammadelta T lymphocytes, whose unique immunosurveillance contributions are analyzed here in different clinical and experimental settings. It is beyond any doubt that the fast, potent, cytotoxic as well as non-cytolytic antiviral activities of gammadelta T cells are critical in protecting the host against diverse viral pathogens.
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