Virus PCR assay panels: an alternative to the mouse antibody production test |
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Authors: | Blank Walter A Henderson Kenneth S White Lisa A |
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Institution: | Charles River Laboratories, 251 Ballardvale Street, Wilmington. MA 01887, USA. |
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Abstract: | Antibody production tests have traditionally been used to test biological materials for viral contamination. Now molecular biology techniques have emerged as an alternative. The authors compare MAP testing with PCR-based detection methods, focusing on differences in animal use, laboratory requirements, sample size, and limits of detection. |
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