Dynamics of the heart minute volume and rheological properties of the blood in the early post-resuscitation period after preagonal and agonal conditions

Fifteen experiments on heparinized (500 IU/kg) dogs (both male and female) under slight nembutal anaesthesia with promedol have revealed that polyglucin hemodilution (60% of blood; 40% of polyglucin) during resuscitation following 4 hours of hypovolemic hypotension prevented the onset of ischemic hyperperfusion syndrome for 5 minutes of post-resuscitation period. Moreover, delayed hyperperfusion syndrome was not observed 3 hours after resuscitation, as it was in animals with blood reinfusion only. Hyperperfusion syndrome was more expressed in animals, recovered after a 4-hour hypovolemic hypotension, than in animals whose agony was caused by a 2-hour arterial hypotension. The correlation was established between high blood viscosity and post-ischemic hyperperfusion (reactive hyperemia).