| 胰岛素样因子(IGF-I)对绵羊毛囊体外培养的研究 |
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| 引用本文： | 李桂芳,赵宗胜,李大全.胰岛素样因子(IGF-I)对绵羊毛囊体外培养的研究[J].生物技术,2005,15(5):28-29. |
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| 作者姓名： | 李桂芳 赵宗胜 李大全 |
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| 作者单位： | 1. 石河子大学生命科学学院
2. 石河子大学动物科技学院,新疆,石河子,832003 |
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| 摘 要： | 对胰岛素样因子（IGF—Ⅰ）对毛囊形态影响及生长调控机理作了初步研究，分别采用0．1ng/mL、1ng／mL、10ng/mL、100ng/mL浓度梯度和对照组，结果表明10ng/／mL IGF—Ⅰ对毛囊生长具有明显的促生长作用，生长速度为0．26mm/d，对其作毛囊生长长度与培养关数进行回归分析，结果表明：培养前8d毛囊生长长度与培养时间呈明显的正相关（P〈0．05）。该试验仅从细胞水平上对体外培养毛囊生长及形态进行了研究，初步证实了IGF—Ⅰ有刺激毛囊生长正向调节作用。
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| 关 键 词： | 体外培养 胰岛素样 毛囊 因子 促生长作用 绵羊 调控机理 浓度梯度 生长速度 |
| 文章编号： | 1004-311X（2005）05-0028-02 |
| 收稿时间： | 2005-06-29 |
| 修稿时间： | 2005-09-06 |
Research on Insulin- like Growth Factor - I(IGF - I) of Hair Follicle Growth in vitro |
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| LI Gui-fang,ZHAO Zong-shong,LI Da-quan.Research on Insulin- like Growth Factor - I(IGF - I) of Hair Follicle Growth in vitro[J].Biotechnology,2005,15(5):28-29. |
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| Authors: | LI Gui-fang ZHAO Zong-shong LI Da-quan |
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| Abstract: | The first research on insulin-like growth factor-I(IGF-I) regulator of hair follicle growth in vitro was made.Respectively adopting 0.1ng/mL,1ng/mL,10ng/mL,100ng/mL degree steps and the controlled,The results showed IGF-I of 10ng/mL obviously promoted hair follicle growth withspeed of 0.26mms/day,made the return analysis to culture days and the hair follicle length.the result was obvious related.(P<0.05).It only studied the culture hair follicle in vitro from the cell level and the appearance,first confirmed the IGF-I inciting the hair follicle growth. |
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| Keywords: | insulin-like growth factor-I hair follicle culture hair follicle appearance |
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