Endocytosis: How dynamin sets vesicles PHree! |
| |
| Authors: | Bottomley M J Lo Surdo P Driscoll P C |
| |
| Affiliation: | Structural Biology Programme, EMBL, Meyerhofstrasse 1, Heidelberg 69117, Germany. |
| |
| Abstract: | The dynamin GTPase is required for clathrin-dependent, receptor-mediated endocytosis. Exciting new studies have shown that dynamin's pleckstrin homology domain binds to phosphatidylinositol 4, 5-bisphosphate in vivo, thus localising dynamin directly at the plasma membrane and ultimately enabling vesiculation. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
