| 212株产β-内酰胺酶葡萄球菌的菌种分布及耐药分析 |
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| 引用本文： | 余一海,彭惠诗,黄木荣. 212株产β-内酰胺酶葡萄球菌的菌种分布及耐药分析[J]. 中国微生态学杂志, 2011, 23(8): 739-741 |
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| 作者姓名： | 余一海 彭惠诗 黄木荣 |
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| 作者单位： | 1. 佛山市顺德区第一人民医院检验科,广东顺德,528300
2. 佛山市顺德区妇幼保健院产科,广东顺德,528300 |
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| 摘 要： | 目的对212株产β-内酰胺酶葡萄球菌的菌种分布和耐药性进行分析,为临床使用抗生素提供依据。方法用Phoenix-100全自动微生物鉴定/药敏系统鉴定分离到的葡萄球菌,并检测其产β-内酰胺酶情况及对20种药物的最低抑菌浓度。用WHONET5.4软件进行数据分析。结果 251株葡萄球菌中产β-内酰胺酶212株,产酶率为84.5%,以金黄色葡萄球菌131株(61.8%),表皮葡萄球菌32株(15.1%),溶血葡萄球菌30株(14.2%)为主。以上菌株除对万古霉素、利奈唑烷、替考拉宁、利福平、呋喃妥因、喹努普汀/达福普汀、甲氧苄胺嘧啶和莫匹罗星敏感外,对其他抗菌素均呈现不同程度耐药,其中青霉素、氨苄西林耐药率均为100%,红霉素为65.1%,苯唑西林53.3%,克林霉素为50.9%,四环素为47.6%。结论临床应积极进行病原学及耐药监测,并在药敏试验结果指导下合理选择抗生素;一旦出现耐甲氧西林金黄色葡萄球菌(MRSA),必须迅速采取控制措施,避免引起医院内感染的暴发流行。
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| 关 键 词： | 葡萄球菌 β-内酰胺酶 药物敏感试验 |
Species distribution and drug resistance of 212 strains of Staphlococcus producing beta-lactamase |
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| YU Yi-hai,PENG Hui-shi,HUANG Mu-rong. Species distribution and drug resistance of 212 strains of Staphlococcus producing beta-lactamase[J]. Chinese Journal of Microecology, 2011, 23(8): 739-741 |
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| Authors: | YU Yi-hai PENG Hui-shi HUANG Mu-rong |
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| Affiliation: | YU Yi-hai1,PENG Hui-shi2,HUANG Mu-rong1(The First People's Hospital of Shunde,Shunde 528300,China,2.Obstetrics Department,Women and Children's Health Center of Shunde,China) |
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| Abstract: | Objective To analyze the species distribution and drug resistance of 212 strains of Staphlococcus producing beta-lactamase in order to provide evidence for proper clinical use of antibiotics.Methods Phoenix-100 automatic microbiological system was applied to perform bacrerial identification;minimal inhibitory concentration(MIC) of 20 antibiotics and beta-lactamase were detected.The results were analyzed by WHONET 5.4 statistical software.Results Among 251 strains of Staphylococcus,212 strains produced beta-... |
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| Keywords: | Staphylococcus Beta-lactamase Microbial sensitivity test |
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