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Metabolites from the endophytic fungus Phomopsis sp. PSU-D15
Authors:Rukachaisirikul Vatcharin  Sommart Ubonta  Phongpaichit Souwalak  Sakayaroj Jariya  Kirtikara Kanyawim
Institution:Department of Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand. vatcharin.r@psu.ac.th
Abstract:From the endophytic fungus Phomopsis sp. PSU-D15, three metabolites named as phomoenamide (1), phomonitroester (2) and deacetylphomoxanthone B (3), were isolated together with three known compounds, dicerandrol A (4), (1S,2S,4S)-p-menthane-1,2,4-triol (5) and uridine. Their structures were elucidated by spectroscopic methods. Phomoenamide (1) exhibited moderate in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Ra.
Keywords:Phomopsis sp    Endophytic fungus  Secondary metabolites  Antimycobacterial activity
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