Department of Cell Biology, HHMI and Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY 10016, USA.
Abstract:
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Highlights? The peroxiredoxin, Jafrac1, controls primordial germ cell adhesion during gastrulation ? H2O2 treatment of Drosophila embryos reduces DE-cadherin and β-catenin levels ? Increasing DE-cadherin levels is sufficient to rescue the Jafrac1 phenotype ? Jafrac1 stabilizes the level of adherens junction components in Drosophila embryos
