Banding and spiralization of human metaphase chromosomes |
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| Authors: | Ranjan Y. Goradia Brian K. Davis |
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| Affiliation: | (1) Department of Biology, Virginia Polytechnic Institute and State University, 24061 Blacksburg, Virginia, USA |
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| Abstract: | Summary A new technique is described which produces spiralization of human metaphase chromosomes. The important feature is heat followed by trypsin treatment. By varying conditions, it is possible to produce bands, spirals and intermediate stages. This provides a new approach to the understanding of banding and chromosome structure. |
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