Ligand-exchange chromatographic resolution ofDl-amino acids in the presence of nucleic acids |
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Authors: | T. Fukuhara S. Yuasa |
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Affiliation: | (1) Department of Biology, College of General Education, Osaka University, 560 Toyonaka, Osaka, Japan |
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Abstract: | Summary Nine representativeDl-amino acids were resolved using ligand-exchange chromatography whose mobile phase containe Cu (II) and ribonucleic acids. It was also found that deoxyribonucleic acids could be substituted for RNAs. In the presence of 5-GMP, 4XMP, (a mixture of 5-GMP,-AMP,-CMP, and-UMP), and oligomer of RNA,L-amino acids, which seemed to give more stable complexes, were eluted more slowly than the opposite isomers. |
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Keywords: | Ligand-exchange chromatography Resolution font-variant:small-caps" >Dl-amino acid Nucleic acid |
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