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Zoster ... "a lmost" ... sine herpete: diagnostic utility of real time-polymerase chain reaction
Authors:Vena Gino A  Apruzzi Doriana  Vestita Michelangelo  Calvario Agata  Foti Caterina  Cassano Nicoletta
Institution:g.vena@dermatologia.uniba.it
Abstract:Zoster sine herpete is a particular form of varicella zoster virus (VZV) infection characterized by segmental pain and dysesthesia, without any cutaneous lesions ever becoming perceptible. This report describes the case of a female patient, presenting with intercostal pain associated with a single papulo-vesicular lesion localized within the same area. Thanks to such a lesion, real time-polymerase chain reaction (PCR) analysis on vesicle fluid swab was possible, thus revealing a significant number of VZV genome copies. This innovative tool has proven essential to diagnose this abortive form of herpes zoster, which would otherwise have remained unidentified.
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