The umbilical cord: a rich and ethical stem cell source to advance regenerative medicine |
| |
Authors: | Forraz N McGuckin C P |
| |
Affiliation: | CTI-LYON, Cell Therapy Research Institute, Parc Technologique de Lyon St Priest, France. |
| |
Abstract: | Science and medicine place a lot of hope in the development of stem cell research and regenerative medicine. This review will define the concept of regenerative medicine and focus on an abundant stem cell source - neonatal tissues such as the umbilical cord. Umbilical cord blood has been used clinically for over 20 years as a cell source for haematopoietic stem cell transplantation. Beyond this, cord blood and umbilical cord-derived stem cells have demonstrated potential for pluripotent lineage differentiation (liver, pancreatic, neural tissues and more) in vitro and in vivo. This promising research has opened up a new era for utilization of neonatal stem cells, now used beyond haematology in clinical trials for autoimmune disorders, cerebral palsy or type I diabetes. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|