职业倦怠与焦虑的相关性及其生物学基础研究

职业倦怠作为当前社会从业人员普遍存在的心理现象,其生理机制主要与长期过度应激引起神经系统的紊乱相关,焦虑与职业倦怠关系密切,都受到神经系统和内分泌系统共同调节。神经系统中神经递质及其受体:如5-羟色胺,去甲肾上腺素和多巴胺的异常,导致焦虑的发生,可能诱发了职业倦怠。本文从激素水平、分子水平、基因水平三个方面分别阐述了职业倦怠发生和焦虑发生的机制以及两者之间相互作用的生物原理,为今后职业倦怠的心理预防以及基因治疗提供了生物医学研究相关的基础理论,也为职业倦怠易感人群,尤其是女性易感人群的焦虑情绪产生的机制研究奠定了详尽的生物医学方面的基础。

Research on the Relevance between Job Burnout and Anxiety and TheirBiological Basis

Burnout of employees is a popular social psychological phenomenon,and its mechanism may mainly be due to the same long-term excessive stress-related nervous system disorders.Burnout and anxiety are closely related with each other and both are regulated by the nervous system and endocrine system.The abnormalities of neurotransmitters and relevant receptors in nervous system such as 5-hydroxytryptamine,norepinephrine and dopamine may lead to anxiety,and further to induce burnout.This paper was ex-pounded the occurrence of job burnout and anxiety in the aspects of hormone level,molecular level and gene level,as well as the interac-tion of the two.It provided some biomedicine related basic theories for job burnout psychological prevention and gene therapy,and also laid biomedicine related foundation for the research of the mechanism of the causes of anxiety for the job burnout-sensitive crowd,espe-cially for the female job burnout-sensitive crowd.