噻托溴铵粉吸入剂治疗稳定期中重度COPD 患者的临床疗效观察

目的:研究噻托溴铵粉吸入剂治疗稳定期中重度COPD患者的临床疗效.方法:选择稳定期中重度COPD患者60例,在患者知情同意的情况下随机均分为对照组(30例)与观察组(30例),对照组患者施行常规药物治疗措施,观察组患者在常规药物治疗措施基础上加用噻托溴铵粉吸入剂治疗,比较两组患者治疗10周后肺功能指标、血气分析指标、呼吸困难评分、生活质量评分及不良反应例数.结果:治疗10周后,两组患者肺功能指标、血气分析指标、呼吸困难评分和生活质量评分比较,差异均具有统计学意义(P＜0.05),观察组优于对照组；发生不良反应例数比较,差异无统计学意义(P＞0.05).结论:在稳定期中重度COPD患者临床治疗过程中,应加用噻托溴铵粉吸入剂治疗,可显著提高临床疗效,且不增加不良反应.

The Clinical Effect Observation of Tiotropium Powder Inhalation in Treating the Patients with Stable Moderate to Severe COPD

Objective: To investigate the clinical effect of tiotropium powder inhalation on treating the patients with stable moderate to severe COPD.Methods: 60 patients with stable moderate were collect to severe COPD,in the case of informed consent.They were divided into the control group(30 cases) and the observation group(30 cases),compared with that the pulmonary function index,blood gas analysis index,dyspnea scores,quality of life scores and adverse reaction cases after ten weeks’ treatment.Results: There was significant statistical difference(P<0.05) in the pulmonary function index,blood gas analysis index,dyspnea scores and quality of life scores after ten weeks’ treatment.The observation group’s clinical effects were better than that in the control group.There was no significant statistical difference(P>0.05) in the adverse reaction cases after ten weeks’ treatment.Conclusion: It should add the tiotropium powder inhalation during treating the patients with stable moderate to severe COPD.It could improve the clinical effect and did not increase the adverse reaction cases.