急性脑梗塞后肺部感染的相关因素及预后

目的:分析探讨急性脑梗塞后肺部感染的相关因素及其预后,以有利于进一步预防及治疗。方法:对2009年5月至2011年5月收治的258例脑梗塞急性期患者的临床资料进行回顾性调查分析,根据是否合并肺部感染分为肺部感染组和对照组,分析肺部感染的危险因素和其预后的相关性。结果:258例脑梗塞患者中发生肺部感染45例,感染率为17.4%,其中心源性脑栓塞占67%。与对照组相比,急性脑梗塞后肺部感染患者年龄偏高(分别为74.2±13.2和69.8±12.7,P<0.021),住院过程中的误吸(OR5.513)及住院时的NIHSS评分(OR1.090)是独立性危险因素,而肺部感染是加重病情的独立性危险因素(OR5.838)。结论:对于高龄、入院时NIHSS评分高、误吸和心源性急性脑梗塞患者应及早预防,已发生肺部感染者应当给予积极有效的治疗。

The Related Risk Factors and Prognosis in Patients with Acute CerebralInfarction Complicated with Pulmonary Infection

Objective: To investigate the related risk factors and prognosis in patients with acute cerebral infarction complicated with pulmonary infection to give better clinical treatment.Methods: The retrospective analysis was performed on the clinical data of 258 patients with acute cerebral infarction in hospital from May 2009 to May 2011.According to whether complicated with pulmonary infection,we classified them into the infection group and control group and investigated the related risk factors and prognosis.Results: Totally 45 cases of pulmonary infection occurred in 258 patients with cerebral infarction(the infection rate 17.4%),among which cardioembolic cerebral infarction was 67%.Compared with the control group,the infection group had a high average age(74.2±13.2 and 69.8±12.7,P<0.021).Aspiration by mistake(OR5.513) and NIHSS(OR1.090) scores were independent risk factors.Pulmonary infection was the independent risk factor of aggravation of the cerebral infarction(OR5.838).Conclusions: For the old patients with aspiration by mistake and high NIHSS scores,and patients with cardioembolic cerebral infarction,we should prevent as soon as possible and give positive and effective treatment.