| Ghrelin 对脑功能的影响 |
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| 引用本文： | 王丽晔,李峰,宋月晗,王万兴,刘燕,马捷,冯婷.Ghrelin 对脑功能的影响[J].现代生物医学进展,2012,12(14):2757-2759. |
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| 作者姓名： | 王丽晔 李峰 宋月晗 王万兴 刘燕 马捷 冯婷 |
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| 作者单位： | 北京中医药大学 北京100029 |
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| 基金项目： | 国家自然科学基金面上项目(30873217);国家自然科学基金项目(81001501);北京市自然基金项目(7112071);教育部高等学校博士学科点专项科研基金(20100013120005);北京中医药大学自主课题(52202)赞助北京中医药大学国家中医药管理局中医科研三级实验室“神经免疫实验室” |
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| 摘 要： | Ghrelin是生长激素促分泌素受体(growth hormone secretagogue receptor,GHSR)的内源性配体,在大鼠胃组织中首次被发现,通过与其特异性受体结合发挥生物学作用。近年来随着对其研究的深入,发现Ghrelin在多种组织中合成分泌,不仅在消化、内分泌等系统产生重要作用,对脑功能也有很大影响,可提高学习记忆能力、影响睡眠、与应激焦虑关系密切并且对脑神经起保护作用。本文总结近几年的文章,旨在通过对Ghrelin对脑功能影响的介绍,为以后的相关研究奠定基础。
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| 关 键 词： | Ghrelin 脑功能 记忆 |
The Influence on Brain Function of Ghrelin |
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| WANG Li-ye,LI Feng,SONG Yue-han,WANG Wan-xing,LIU Yan,MA Jie,FENG Ting.The Influence on Brain Function of Ghrelin[J].Progress in Modern Biomedicine,2012,12(14):2757-2759. |
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| Authors: | WANG Li-ye LI Feng SONG Yue-han WANG Wan-xing LIU Yan MA Jie FENG Ting |
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| Institution: | (Beijing University of Chinese Medicine,100029,Beijing,China) |
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| Abstract: | Ghrelin is the endogenic ligand of growth hormone secretagogue receptor(GHSR),which was firstly detected in stomach of mouse and played a role in combing with specificity receptor.Research in recent years showed that Ghrelin was synthesised and secreted in many tissues.Besides the influence on digestive system and endocrine system,it can also effect on brain function,such as increasing learning abilities,influencing on sleep quality and emotion,protecting the cranial nerves.The article summarizes many papers published in recent years in order to lay the foundation of correlational investigation through the introduction of influence on brain function of Ghrelin. |
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| Keywords: | Ghrelin Brain function Memory |
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