脑钠肽临床应用进展

脑钠肽(brain natriuretic peptide,BNP)是近年倍受关注的心血管生物标记物,BNP是一种主要由心脏分泌的肽类激素,在心脏维持其正常结构和功能的中起着重要的作用,它具有利钠、利尿、扩血管、降压、拮抗RAAS系统、抑制交感神经兴奋等作用.它已超过原来仅作为心衰的诊断检测指标范畴.研究表明BNP与呼吸困难的鉴别诊断、心肌梗死、高血压、心房颤动、心肌病、肺栓塞等关系密切,现就BNP的临床研究进展作一综述.

Advances in Clinical Application of Brain Natriuretic Peptide

Brain natriuretic peptide(BNP) is one of the most attentive cardiovascular physiological biomarkers in recent years,It is a major peptide hormone secreted by the heart,and it plays an important compensatory role in maintaining heart normal structure and function.It’s has satisfaction row,urination,vasodilators,and lowering blood pressure and so on in the human body,inhibitting RAAS system and sympathetic nervous system.BNP has a closing relationship with differential diagnosis of dyspnea,myocardial infarction,hy-pertension,fibrillation,cardiomyopathy,pulmonary embolism and so on.Now this paper will reviewe on BNP’s research progress.