3 例以延髓麻痹为首发表现的肌萎缩侧索硬化的病例报告

目的:探讨以延髓麻痹为首发症状的肌萎缩侧索硬化的临床特点。方法:报告3例以构音障碍等延髓麻痹症状起病的肌萎缩侧索硬化少见病例,结合文献复习,分析其临床特点。结果:在ALS患者中,以延髓麻痹为首发症状发生率相对较低,多见于老年人,最易表现为构音障碍,患者的生存期缩短,预后不良。结论:对于以延髓麻痹表现起病的ALS患者,要引起重视,及时针对延髓麻痹对症治疗,改善患者生活质量。

A Report of 3 Cases: Amyotrophic Lateral Sclerosis (ALS) with Onset of Bulbar Palsy

Objective: Discuss the clinical feature of ALS with onset of bulbar palsy.Methods: Report 3 rare cases of ALS with onset of bulbar palsy symptoms such as dysarthria,and analysed its clinical features combined with literature review.Results: In ALS pa-tients,bulbar pulsy as the first symptom is relative rare,and patients were apt to display the symptoms of dysarthria with shortened longevi-ty and poor prognosis.Conclusions: For the ALS patients with onset of bulbar palsy symptoms,we should pay more attention to promptly symptomatic treatment for bulbar paralysis so as to improve the quality of life.