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急性传染病休克的临床诊治与转归分析
引用本文:姜天俊,辛绍杰,郭晓东,游绍莉,张昕,涂波,徐哲,李丰衣,聂为民,赵敏,李进.急性传染病休克的临床诊治与转归分析[J].现代生物医学进展,2012,12(22):4288-4290.
作者姓名:姜天俊  辛绍杰  郭晓东  游绍莉  张昕  涂波  徐哲  李丰衣  聂为民  赵敏  李进
作者单位:1. 解放军第三零二医院感染病诊疗与研究中心 北京100039
2. 解放军第三零二医院医务部 北京100039
3. 解放军第三零二医院肝衰竭中心 北京100039
4. 解放军第三零二医院病理科 北京100039
基金项目:国家科技重大专项(2010ZXJ0900X-004-002)
摘    要:目的:探讨急性传染病休克患者的诊治策略,提高救治成功率.方法:回顾分析急性传染病休克患者的人口学、流行病学、病因分类、传染病发生至休克出现时间、早期临床诊治与转归等情况,总结诊治经验.结果:本组68例急性传染病休克主要来自呼吸道、消化道传染病,细菌和病毒是休克发生的主要病原,分别占54.4%和30.9%,仅25%的病例病前有明确的传染病接触史.51.9%的患者存在误诊误治现象.在明确休克发生病理机制的前提下,早期快速有效的抗休克、抗感染治疗,短期使用糖皮质激素,积极纠正酸碱、电解质紊乱,并给予必要的对症支持治疗,治愈出院率92.6%,平均康复住院时间3~11天,平均(5.8±2.4)天.结论:急性传染病休克早期误诊现象突出;给予积极抗体克、抗感染、激素治疗,纠正酸碱和电解质紊乱,结合对症支持治疗,可在短期内治愈患者.

关 键 词:传染病  急性  休克  诊断  治疗

The Diagnosis and Emergency Treatment of Patients with Acute Infectious Shock
JIANG Tian-jun,XIN Shao-jie,GUO Xiao-dong,YOU Shao-li,ZHANG Xin,TU Bo,XU Zhe,LI Feng-yi,NIE Wei-min,ZHAO Min,LI Jin.The Diagnosis and Emergency Treatment of Patients with Acute Infectious Shock[J].Progress in Modern Biomedicine,2012,12(22):4288-4290.
Authors:JIANG Tian-jun  XIN Shao-jie  GUO Xiao-dong  YOU Shao-li  ZHANG Xin  TU Bo  XU Zhe  LI Feng-yi  NIE Wei-min  ZHAO Min  LI Jin
Institution:1 The Treatment and Research Center for Infectious disease,302 Hospital of PLA,Beijing 100039,China;2 The Treatment and Research Center for Live Failure,302 Hospital of PLA,Beijing,100039,China;3 The Department of pathology,302 Hospital of PLA,Beijing,100039,China;4 The Medical Department,302 Hospital of PLA,Beijing,100039,China)
Abstract:Objective:To explore the strategy of diagnosis and treatment of shock in patients with acute infectious diseases,improve the rescue success rate.Methods:The clinical data,including demographic,epidemiology,etiology,the period of infectious diseases oc-currence to the shock appearance,early clinical diagnosis and treatment,and outcome,of 68 patients with acute infectious diseases were analysed.Results:The group of 68 cases of acute infectious diseases shock were mainly from the respiratory tract,gastrointestinal dis-eases.Bacteria and viruses were the main pathogens of the shock,which accounted for 54.4% and 30.9%,respectively.Only 25% of cas-es had a clear history of exposure of infectious diseases before.51.9% of patients had been misdiagnosed.On the basis of a clear patho-genesis of shock,early fast and effective anti-shock,anti-infective therapy,short-term use of corticosteroids,and actively correct the pH,electrolyte imbalance,and necessary support for symptomatic treatment were given.The cured rate was 92.6% and the rehabilitation length of stay was 3 to 11 days,the average(5.8 ±2.4) days.Conclusion:Misdiagnosed phenomenon highlights the acute infectious stage of shock.With positive anti-shock,anti-infective,hormone therapy,correcting acid-base and electrolyte imbalance,combined with symptomatic and supportive treatment,the patients can be cured in a short term.
Keywords:Infectious disease  Acute  Shock  Diagnosis  Treatment
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