黄芪注射液联合TP 化疗方案治疗晚期卵巢癌的临床疗效分析*

目的:观察黄芪注射液联合TP化疗方案治疗晚期卵巢癌的临床疗效及安全性.方法:将62例晚期卵巢癌患者随机分成两组,其中31人为治疗组,接受黄芪注射液联合TP治疗,31人采用TP治疗.从总效率、疾病控制、毒副反应等指标进行评价.结果:治疗组的总效率、疾病控制、骨髓抑制以及肝肾功能与对照组相比,差异无统计学意义(P＞0.05)；治疗组的中性粒细胞、心脏毒性、脱发、肌肉关节疼痛、胃肠道反应与对照组相比,差异有统计学意义(P＜0.01).结论:黄芪注射液联合TP化疗方案治疗晚期卵巢癌的临床疗效显著,降低了化疗的毒副反应.

Clinical Effect of the Advanced Ovarian Cancer Treated by Huangqi InjectionCombined with TP Regimen*

Objective: To explore clinical efficacy and safety of advanced ovarian cancer treated by Huangqi injection combined with TP Regimen.Methods: 62 patients with advanced ovarian cancer were randomly divided into the treating group(31people) and control group(31 people).The treating group was treated with Huangqi injection combined with TP Regimen;the control group was only applied to TP Regimen.The clinical efficacy and safety were evaluated by calculating the total effect rate,disease control rate and observing the toxicity reaction.Results: There is no statistical difference in total effect rate,disease control rate,bone marrow supression and function of liver and kidney between the two groups(P >0.05).Compared with control group,the treating group showed significant difference in Neutrocytopenia,cardiac toxicity,Hair loss,Muscle and joint ache,and Gastrointestinal reaction(P <0.05).Conclusion: Huangqi injection plus TP Regimen had markedly clinical efficacy in treating the advanced ovarian cancer.It also plays a role in reducing the toxicities of chemotherapy.