Limited proteolysis of actin by a specific bacterial protease |
| |
Authors: | T D Khaitlina SYu Y" >Smirnova,A M Usmanova |
| |
Affiliation: | Institute of Cytology, USSR Academy of Sciences, Leningrad. |
| |
Abstract: | A 36 kDa fragment of rabbit skeletal muscle actin resistant to further proteolytic breakdown was obtained with a new bacterial protease. This fragment was the only cleavage product obtained from native actin whereas proteolysis of heat-inactivated actin was unlimited. The 36 kDa fragment failed to polymerize and to inhibit DNase I activity. Binding to DNase I protects actin against proteolysis by protease. The results on actin proteolysis by different proteases are compared. |
| |
Keywords: | |
|
|