31P-NMR study of the levels of phosphorus-containing metabolites in the mouse liver during administration of highly dispersed zinc powder

The content of phosphor-containing metabolites as regards inorganic phosphate of tissues of the mouse liver after injection of zinc highly dispersed powder at the dose of 5 mg/kg has been established with quantitative calculation of 31P-NMR spectra. A decrease in the relative level of phosphor-containing metabolites in the liver regeneration on the first day after partial hepatectomy has been observed. It has been shown that the relative level of phosphor-containing metabolites after injection more decreased during the first two days after operation. The observed changes of P-compounds metabolites in the liver after injection of zinc highly dispersed powder are related to its stimulation effect on metabolism of sugar and phospholipids and on the cell respiratory process.