Fine-scale genetic diversity among Burkholderia pseudomallei soil isolates in northeast Thailand |
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Authors: | U'ren Jana M Hornstra Heidie Pearson Talima Schupp James M Leadem Benjamin Georgia Shalamar Sermswan Rasana W Keim Paul |
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Affiliation: | Northern Arizona University, Department of Biological Sciences, Box 5640, Flagstaff, AZ 86011-5640, USA. |
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Abstract: | Burkholderia pseudomallei soil isolates from northeast Thailand were genotyped using multiple-locus variable-number tandem repeat (VNTR) analysis (MLVA) and multilocus sequence typing (MLST). MLVA identified 19 genotypes within three clades, while MLST revealed two genotypes. These close genetic relationships imply a recent colonization followed by localized expansion, similar to what occurs in an outbreak situation. |
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