Assignment of the gene encoding DNA ligase I to human chromosome 19q13.2-13.3. |
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Authors: | D E Barnes K Kodama K Tynan B J Trask M Christensen P J De Jong N K Spurr T Lindahl H W Mohrenweiser |
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Affiliation: | Imperial Cancer Research Fund, Clare Hall Laboratories, South Mimms, Hertfordshire, United Kingdom. |
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Abstract: | The gene encoding DNA ligase I has been mapped on human chromosome 19 by analysis of rodent-human somatic cell hybrids informative for this chromosome and by two-color fluorescence in situ hybridization. The DNA ligase I gene (LIG1) is localized to 19q13.2-13.3 and is distal to ERCC1, the most telomeric of three DNA repair genes on this chromosome. |
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