The FI gene product of bacterial virus Lambda is related to theE. coli chromosomal protein NS2 and is involved in intracellular DNA organization |
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| Authors: | H. Witkiewicz R. Schneider M. Schweiger |
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| Affiliation: | (1) Present address: Department of Medical Biochemistry, University of Calgary, 3330 Hospital Dr N.W., T2N 4N1 Calgary, Alberta, Canada |
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| Abstract: | A likely function of the Lambda FI gene product (gpFI) is condensation of developmental forms of the bacteriophage DNA in the host cell. Several characteristics of gpFI support this hypothesis: it is similar in its structure and properties toE. coli NS proteins whose involvement in the bacterial DNA condensation has been established and it comigrates with DNA during fractionation of host cell lysate through a sucrose gradient. |
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| Keywords: | DNA condensation DNA protein-interaction genome organization nucleoid structure protein homologies |
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