BFA effects are tissue and not just plant specific |
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Authors: | Robinson David G Langhans Markus Saint-Jore-Dupas Claude Hawes Chris |
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Affiliation: | Department of Cell Biology, Heidelberg Institute for Plant Sciences, University of Heidelberg, 69120 Heidelberg, Germany. |
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Abstract: | Brefeldin A (BFA) is one of the most popular drugs used by researchers for studies on secretion and endocytosis because it interferes with specific vesicle coat proteins via action on a guanine nucleotide exchange factor. Due to its range of morphological effects on the Golgi apparatus in a variety of plant tissues, we believe that there is more to the BFA response than the primary molecular targets so far identified. |
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