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Role of recombination occurring during DNA replication |
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| Authors: | V. V. Sukhodolets |
| Affiliation: | (1) State Research Center GosNIIgenetika, Moscow, 117545, Russia |
| Abstract: | Unequal crossing over between direct DNA repeats of sister chromosomes occurs during DNA replication in Escherichia coli. Such exchanges yield tandem duplications and thereby increase the expression of the genes involved. Nonhomologous cohesion of sister chromosomes and unequal crossing over were assumed to take place when the replication fork stops. When the replication forks moves continuously, homologous exchanges between sister chromosomes ensure their postreplication repair. |
| Keywords: | DNA replication recombination replication fork RuvABC RecG Holliday junction Escherichia coli unequal crossing over tandem duplication nonhomologous cohesion of sister chromosomes |
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