Comparison of photodynamic effect with respect to human and rabbit erythrocytes |
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| Authors: | L. V. Galebskaya I. L. Solovtsova D. B. Zammoeva A. N. Kuzmenkov |
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| Affiliation: | (1) Institute of Medical Microbiology and Hygiene, University of Mainz, Augustusplatz, 55101 Mainz, Germany;(2) Molecular Microbiology and Genomics Consultants, Zotzenheim, Germany |
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| Abstract: | Parameters of photoinduced lysis are studied in human and rabbit erythrocytes (photosensitizer-Radachlorine, the light source Shatl, λ = 633 nm). The higher sensitivity to irradiation is revealed in rabbit erythrocytes. Treatment of erythrocytes with trypsin showed the surface proteins in human cells to produce a protective action. Trypspnization of rabbit erythrocytes produced the opposite effect-the rate of photohemolysis increased. Results of the study indicate the differences in sensitivity to the photoinduced lysis of erythrocytes of different species and participation of erythrocyte proteins in the effect of photohemolysis. |
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