Role of metallothioneins in metal regulation by the guillemot Uria aalge |
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| Institution: | 2. Canadian Forest Service, Natural Resources Canada, Quebec City, Canada;3. Idaho National Laboratory, Idaho Falls, ID, United States of America;1. Center for Translational Injury Research and Division of Acute Care Surgery, Department of Surgery, Medical School, University of Texas Health Science Center at Houston, 6431 Fannin St. MSB 5.240, Houston, TX 77030, USA;2. Division of Trauma, Critical Care and Acute Care Surgery, School of Medicine, Oregon Health & Science University, 3181 Sam Jackson Rd SW, Mail Code L-611, Portland, OR 97035, USA;3. Division of Trauma/Critical Care, Department of Surgery, College of Medicine, University of Cincinnati, 222 Piedmont Ave., Suite 7000, Cincinnati, OH 45219, USA;4. Division of Clinical and Translational Sciences, Department of Internal Medicine, Medical School, Biostatistics/Epidemiology/Research Design Core,Center for Clinical and Translational Sciences and Division of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, 1100 Fannin St. UPB 1100.21, Houston, TX 77030, USA;5. Division of General Surgery, Department of Surgery, School of Medicine, University of California San Francisco, 1001 Potrero Ave. Room 3C-38, San Francisco, CA 94110, USA |
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| Abstract: | Guillemots, like other seabird species living in the North Sea, appear to be heavily contaminated by copper. Metallothioneins are present in both liver and kidney but, at least in the specimens stranded along the Belgian coast, fail to maintain constant the copper, zinc and cadmium load of the high molecular weight soluble proteins of both organs, stressing the potential toxic role of these metals, mainly copper. |
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