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The electronic structure and radiorprotective activity of a series of substituted iminodihydrofurans] |
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| Authors: | E E Khutorskaia G S Beloglazov E L Izmozherova A N Filaretov Iu M Skvortsov |
| Abstract: | Compounds that increase the survival rate of lethally exposed hybrid (CBA x C57B1/6)F1 mice have been revealed within the series of iminodihydrofurans. The quantum-chemical estimates, made by the MNDO method, show that substances which are capable of donor-acceptance interaction with DNA nucleotides and have the energy of donor orbitals, comparable with the electron structure of nucleotides, possess radioprotective efficacy. |
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