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人免疫缺陷病毒母婴传播研究进展
引用本文:孙利,张久聪,何文革,孙永涛. 人免疫缺陷病毒母婴传播研究进展[J]. 生物技术通讯, 2010, 21(3): 424-427,437. DOI: 10.3969/j.issn.1009-0002.2010.03.029
作者姓名:孙利  张久聪  何文革  孙永涛
作者单位:第四军医大学,唐都医院传染病科,全军感染病诊疗中心,陕西,西安,710038
基金项目:陕西省自然科学基金社发攻关项目 
摘    要:随着抗逆转录病毒药物和抗蛋白酶抑制剂的联合应用,人免疫缺陷病毒(HIV)的垂直传播率可降至2%以下。尽管如此,据估计全世界每天仍有1600名婴儿感染HIV。因此,研究HIV母婴传播中的危险因素和干预措施,仍然是极为重要的防治垂直传播的课题。我们就HIV母婴传播的最新进展做简要综述。

关 键 词:人免疫缺陷病毒  母婴传播  传播途径  干预措施

Recent Advance in HIV Mother-to-Infant Transmission
SUN Li,ZHANG Jiu-Cong,HE Wen-Ge,SUN Yong-Tao. Recent Advance in HIV Mother-to-Infant Transmission[J]. Letters in Biotechnology, 2010, 21(3): 424-427,437. DOI: 10.3969/j.issn.1009-0002.2010.03.029
Authors:SUN Li  ZHANG Jiu-Cong  HE Wen-Ge  SUN Yong-Tao
Affiliation:The PLA Centre for Infectious Disease Diagnosis and Treatment,Tangdu Hospital,Fourth Military Medical Univer-sity,Xi'an 710038,China
Abstract:With the availability of antiprotease inhibitors used in combination with other antiretrovirals,human im-munodeficiency virus(HIV) vertical transmission can be reduced to less than 2%.In spite of these advances,it is estimated that daily 1600 infants are still being infected with HIV-1 perinatally worldwide.Thus,understanding the risk factors associated with mother-to-infant transmission remains critically important for the development of im-proved strategies for the prevention of vertical transmission.In this paper,we discussed recent advance in HIV mother-to-infant transmission.
Keywords:human immunodeficiency virus  mother-to-infant transmission  transmission resources  intervention
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