Purification and characterization of enterocin 4, a bacteriocin produced by Enterococcus faecalis INIA 4. |
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Authors: | H M Joosten M Nunez B Devreese J Van Beeumen and J D Marugg |
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Abstract: | A simple two-step procedure was developed to obtain pure enterocin 4, a bacteriocin produced by Enterococcus faecalis INIA 4. Chemical and genetic characterization revealed that the primary structure of enterocin 4 is identical to that of peptide antibiotic AS-48 from Enterococcus faecalis S-48. In contrast to the reported inhibitory spectrum of AS-48, enterocin 4 displayed no activity against gram-negative bacteria. |
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