Bacterial transposon Tn5: evolutionary inferences |
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Authors: | Berg DE; Berg CM; Sasakawa C |
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Institution: | Department of Microbiology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63110. |
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Abstract: | Transposable elements induce spontaneous mutations, promote genome
rearrangements, regulate gene expression, and participate in the horizontal
spread of genes encoding traits such as antibiotic resistance among
bacterial genera too distantly related to undergo homologous recombination.
Here we review the bacterial transposon Tn5 and focus on those aspects of
its functional organization and transposition which provide insights into
how it and other elements may have arisen, proliferated, and evolved.
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