Reparative processes in postischemic cerebral cortex in the early postresuscitation period (materials submitted to the International Symposium, "Central nervous system and postresuscitation pathology," Moscow, March 14-16, 1989)

Dynamics of neuronal plasticity in rat postischemic cerebral cortex in the early postresuscitation period following complete ischemia was studied by electron microscopic methods. In this period destructive processes have proved to run parallel with reparative ones in the postischemic cerebral cortex. The phenomenon of true regeneration of cell processes in the cerebral neurons engendering growth cones observed by the third hour of the post-resuscitation period is of particular interest. Subsequently, these signs lead to the formation of new synaptic interneuronal links and new neuronal nets in the cerebral cortex. The data obtained open up new prospects for understanding the pathogenesis of postresuscitation encephalopathies.