Characterization of the AXH domain of Ataxin‐1 using enhanced sampling and functional mode analysis期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Characterization of the AXH domain of Ataxin‐1 using enhanced sampling and functional mode analysis

Authors:	Jack A. Tuszynski Diana Massai Diego Gallo Umberto Morbiducci Andrea Danani

Affiliation:	1. Department of Physics, University of Alberta, Edmonton, Alberta, Canada;2. Department of Mechanical and Aerospace Engineering, Politecnico Di Torino, Torino, Italy;3. Department of Cardiothoracic, Transplantation, and Vascular Surgery (HTTG), Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Hannover Medical School, Hannover, Germany;4. Istituto Dalle Molle Di Studi Sull'intelligenza Artificiale (IDSIA), Scuola Universitaria Professionale Della Svizzera Italiana (SUPSI), Università Della Svizzera Italiana (USI), Manno, Switzerland

Abstract:

Keywords:	neurodegenerative replica exchange molecular dynamics Ataxin functional mode analysis protein− protein interactions dimer AXH conformational stability