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Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC
Authors:Ying Liu  Tuhin Bhowmick  Yiqiong Liu  Xuefan Gao  Haydyn DT Mertens  Dmitri I Svergun  Junyu Xiao  Yan Zhang  Jia-huai Wang  Rob Meijers
Institution:1. State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing 100871, China;2. European Molecular Biology Laboratory (EMBL), Hamburg Outstation, Notkestrasse 85, D-22607 Hamburg, Germany;3. PKU-IDG/McGovern Institute for Brain Research, Peking University, 100871 Beijing, China;4. State Key Laboratory of Protein and Plant Gene Research, School of Life Science and Peking-Tsinghua Centre for Life Sciences, Peking University, 100871 Beijing, China;5. Department of Medical Oncology and Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
Abstract:
Keywords:Netrin  deleted in colorectal cancer  DCC  Draxin  fasciculation  axon guidance  crystal structure  cysteine knot domain  guidance cue  adhesion
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