| 超嗜热古菌基因组的热稳定性 |
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| 引用本文： | 盛多红.超嗜热古菌基因组的热稳定性[J].生命科学,2014(1):64-71. |
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| 作者姓名： | 盛多红 |
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| 作者单位： | 山东大学微生物技术国家重点实验室,济南250100 |
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| 基金项目： | 山东省优秀中青年科学家科研奖励基金项目（BS2010SW014） |
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| 摘 要： | 超嗜热古菌能够生活在80℃以上的高温环境中,它们的耐热性已经成为当前研究的热点之一。以往对超嗜热菌的认识多集中于蛋白质的耐热性,而很少有关于基因组热稳定性的综述文章。综述了当前对超嗜热古菌的基因组稳定性以及DNA损伤识别机制的研究进展,以期更好地了解超嗜热古菌的耐热机制。
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| 关 键 词： | 超嗜热古菌 基因组稳定性 DNA损伤诱导反应 DNA修复 |
The genomic thermostability of hyperthermophilic archaea |
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| SHENG Duo-Hong.The genomic thermostability of hyperthermophilic archaea[J].Chinese Bulletin of Life Sciences,2014(1):64-71. |
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| Authors: | SHENG Duo-Hong |
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| Institution: | SHENG Duo-Hong (State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, China) |
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| Abstract: | Hyperthermophilic archaea is adapted to live at temperatures higher than 80℃. Their thermotolerance has become a research hotspot. Previous publications on the archaeal heat-resistant mechanism primarily focused on protein, and rarely on the genomic thermostability. Here, we reviewed the research progress on the genomic stability and DNA damage response of hyperthermophilic Archaea, and hoped to be helpful to better understand the archaeal thermostability. |
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| Keywords: | hyperthermophilic archaea genomic stability DNA damage response DNA repair |
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