Orientia tsutsugamushi infection: overview and immune responses |
| |
Authors: | Seong S Y Choi M S Kim I S |
| |
Institution: | Department of Microbiology and Immunology, Seoul National University College of Medicine and Institute of Endemic Disease, Seoul National University Medical Research Center, 28 Yongon-dong, Chongno-gu, 110-799, Seoul, South Korea. |
| |
Abstract: | Orientia tsutsugamushi, an obligate intracellular bacterium, was isolated for the first time in 1930. Infections by virulent strains are characterized by fever, rash, eschar, pneumonia, myocarditis, and disseminated intravascular coagulation. Here we review the general aspects of O. tsutsugamushi and immune responses in terms of inflammation, protective immune mechanisms, and immunogenic antigens. |
| |
Keywords: | |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|