Serologic and virologic analysis of type D simian retrovirus infection in a colony of Celebes black macaques (Macaca nigra) |
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Authors: | S Shiigi B Wilson G Leo N MacDonald D Toyooka L Hallick R Karty M L Belozer W McNulty J Wolff |
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Institution: | Division of Primate Medicine, Oregon Regional Primate Research Center, Beaverton. |
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Abstract: | Celebes macaques were tested for type D simian retrovirus (SRV) infection. SRV infection was first detected in one serum sample collected during 1980. By 1983, 32 of 46 monkeys (70%) were infected. Serotyping of the SRV isolates determined that 0/26 of the isolates were SRV-1; 24/26 were SRV-2; 1/26 was SRV-5; and 1/26 could not be typed. Restriction endonuclease mapping confirmed the SRV-2C and SRV-5 isolates. In addition, two SRV-2C variants were detected. |
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Keywords: | Membrane immunofluorescence Virus isolation Restriction mapping SRV variants Epidemiology |
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