Effects of early electrical stimulation of the lateral hypothalamus on the delayed acquisition of approach and avoidance learning tasks in the rat |
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Authors: | Lydia Velley Gérard Manciet Bernard Cardo |
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Affiliation: | Laboratoire de Psychophysiologie, Institut de Biologie Animale, Université de Bordeaux 1, Avenue des Facultés, 33405 Talence Cedex France |
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Abstract: | Three experiments indicated the effects of an early bilateral stimulation of the lateral hypothalamus on later learning behaviour of male rats. The animals were stimulated at 15 days of age and tested during the sixth week of life. Stimulated rats showed an improvement of performances in acquisition of a food-reinforced operant conditioning, but their performance was impaired in two avoidance tests, an inhibitory avoidance response and a two-way avoidance test. These results cannot be interpreted in terms of handling or early experience. An hypothesis of a modified synaptic competition favouring circuits which assure the regulation of approach behaviours is formulated. |
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