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Oxidative stress and S-100B protein in children with bacterial meningitis |
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| Authors: | Sherifa A Hamed Enas A Hamed Madeha M Zakary |
| Affiliation: | (1) Department of Neurology, Faculty of Medicine, Assiut University, Assiut, Egypt;(2) Department of Physiology, Faculty of Medicine, Assiut University, Assiut, Egypt;(3) Department of Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt |
| Abstract: | BackgroundBacterial meningitis is often associated with cerebral compromise which may be responsible for neurological sequelae in nearly half of the survivors. Little is known about the mechanisms of CNS involvement in bacterial meningitis. Several studies have provided substantial evidence for the key role of nitric oxide (NO) and reactive oxygen species in the complex pathophysiology of bacterial meningitis. |
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