Identification of a potent and rapidly reversible inhibitor of the 20S-proteasome |
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Authors: | Purandare Ashok V Wan Honghe Laing Naomi Benbatoul Khalid Vaccaro Wayne Poss Michael A |
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Affiliation: | Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ 08543, USA. ashok.purandare@bms.com |
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Abstract: | Synthesis and in vitro characterization of novel, lactam boronic acid based, selective, and rapidly reversible inhibitor 14 of the 20S-proteasome is presented. |
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