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Identification of a potent and rapidly reversible inhibitor of the 20S-proteasome
Authors:Purandare Ashok V  Wan Honghe  Laing Naomi  Benbatoul Khalid  Vaccaro Wayne  Poss Michael A
Affiliation:Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ 08543, USA. ashok.purandare@bms.com
Abstract:Synthesis and in vitro characterization of novel, lactam boronic acid based, selective, and rapidly reversible inhibitor 14 of the 20S-proteasome is presented.
Keywords:
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