Bovine attaching and effacing Escherichia coli possess a pathogenesis island related to the LEE of the human enteropathogenic Escherichia coli strain E2348/69 |
| |
| Authors: | Frederic Goffaux Jacques Mainil Vinciane Pirson Gerard Charlier Pierre Pohl Etienne Jacquemin Bernard China |
| |
| Institution: | University of Liège, Faculty of Veterinary Medicine, Laboratory of Bacteriology, Sart Tilman B43, B-4000 Liège, Belgium;National Institute for Veterinary Research, Groeselenberg 99, B-1180 Brussels, Belgium |
| |
| Abstract: | Attaching and effacing Escherichia coli (AEEC) has been described as a cause of diarrhea in calves. The molecular pathogenesis of AEEC was mainly studied in human enteropathogenic E. coli strain E2348/69 in which the virulence correlated with the presence of a 35.4 kb pathogenesis island called LEE. We showed that several strains isolated from calves with diarrhea were able to produce attaching and effacing lesions in a rabbit ileal loop model and that they possess a pathogenesis island related to the LEE. Moreover, we showed that the LEE from bovine strains was inserted mainly at a different position in the chromosome compared to the human enteropathogenic E. coli strain E2348/69. |
| |
| Keywords: | Bovine attaching effacing Escherichia coli Pathogenesis island LEE |
| 本文献已被 ScienceDirect 等数据库收录！ |
