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Applanoxidic acids A, B, C and D, biologically active tetracyclic triterpenes from Ganoderma applanatum |
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| Authors: | Chairul Takashi Tokuyama Yoshinori Hayashi Mugio Nishizawa Harukuni Tokuda Sofni M. Chairul Yuji Hayashi |
| Affiliation: | a Faculty of Science, Osaka City University, Osaka 558, Japan b R&D Centre for Biology (LIPI), Juanda 18, Bogor, Indonesia c Tokushima Bunri University, Tokushima 770, Japan d Department of Biochemistry, Kyoto Prefectural University of Medicine, Kyoto 602, Japan e The Centre for Isotope Application and Radiation, National Atomic Agency, Ps-Jum'at, Jakarta, Indonesia |
| Abstract: | Four novel polyoxygenated lanostanoid triterpenes, named applanoxidic acids A, B, C, and D, have been isolated from an Indonesian tropical fungus, Ganoderma applanatum. Their structures were determined by spectrocopic and chemical methods. Biological activity as an anti-tumour promoter was observed for these components. |
| Keywords: | Ganoderma applanatum Polyporaceae triterpenes applanoxidic acids A, B, C and D anti-tumour promoters. |
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