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人多肽链延伸因子1α四个反转录假基因的鉴别与定位
引用本文:崔峰,刘春宇,夏家辉CUI Feng,LIU Chun-yu,XIA Jia-hui. 人多肽链延伸因子1α四个反转录假基因的鉴别与定位[J]. 遗传, 1998, 20(6): 6-10
作者姓名:崔峰  刘春宇  夏家辉CUI Feng  LIU Chun-yu  XIA Jia-hui
作者单位:长沙湖南医科大学医学遗传学国家重点实验室, 湖南 410078National Laboratory of Medical Genetics,Human Medical University,Changsha 410078
摘    要:人多肽链延伸因子1α基因EEF1A是一个在蛋白质合成过程中起重要作用的看家基因。通过对已有GenBank、GDB等数据库的综合分析,鉴别了4个人类多肽链延伸因子1α基因的反转录假基因,并分别将其精细定位于4q2 5、7p15-21、9q34和19q13上。Abstract:The gene for human polypeptide chain elongation factor-1α(EEF1A)is a house-keeping gene which plays an important role in the process of protein synthesis.By means of comprehensive analysis in the database of Genbank,GDB and ect,we identify 4 retropseudogenes of EEF1A and finely localized to 4q25,7p15-21,9q34 and 19q13,respectively.

关 键 词:定位 Key words  Retropseudogene  Polypeptide chain elongation factor-1α  反转录假基因  多肽链延伸因子1α  Downs综合征  21号染色体  减数分裂起源  GT重复多态性  不分离  

Identification and Localization of 4 Retropseudogenes of theHuman Polypeptide Chain Elongation Factor-1(alpha)
CUI Feng LIU Chunyu XIA Jiahui. Identification and Localization of 4 Retropseudogenes of theHuman Polypeptide Chain Elongation Factor-1(alpha)[J]. Hereditas, 1998, 20(6): 6-10
Authors:CUI Feng LIU Chunyu XIA Jiahui
Abstract:
Keywords:Down Syndrome  Meiotic origin  (GT) n polymorphism  Chromosome 21  Nondisjunction
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