Adenovirus vectors for gene expression. |
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| Authors: | M V Chengalvala M D Lubeck B J Selling R J Natuk K H Hsu B B Mason P K Chanda R A Bhat B M Bhat S Mizutani |
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| Affiliation: | Wyeth-Ayerst Research, Philadelphia, Pennsylvania. |
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| Abstract: | Adenoviruses possess a combination of features that make them highly suitable as vectors for expression of heterologous genes. Non-conditional and non-defective adeno-vectors have been constructed to obtain high level expression of a number of foreign genes and some of them have been shown in animal models to exhibit excellent promise as vaccine candidates. |
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