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Difference in the inhibitory effect of linoleic acid hydroperoxide on prostacyclin biosynthesis between cultured endothelial cells from human umbilical cord vein and cultured smooth muscle cells from rabbit aorta |
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| Authors: | Y Sasaguri M Morimatsu T Nakashima O Tokunaga K Yagi |
| Abstract: | The biosynthesis of prostacyclin in cultured endothelial cells from human umbilical cord vein was inhibited by linoleic acid hydroperoxide at a concentration of 0.1 nmol/ml (in terms of malondialdehyde), while that in cultured smooth muscle cells from rabbit aorta was inhibited only at a higher concentration of the hydroperoxide (5.0 nmol/ml). |
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