Carbohydrate histochemistry of human Brunner's glands |
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| Authors: | A Crescenzi P Barsotti L Anemona V Marinozzi |
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| Affiliation: | I Cattedra di Anatomia ed Istologia Patologica, Dipartimento di Biopatologia Umana, Università, La Sapienza, Roma, Italy. |
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| Abstract: | Brunner's glands are known to produce neutral mucins. In order to achieve a better knowledge of their carbohydrate profile, we used five peroxidase-labeled lectins on surgical specimens of human duodenum. This method allowed us to identify at least two different types of neutral mucins in Brunner's glands secretion, thus demonstrating a heterogeneous mucin production. The structure of terminal oligosaccharidic chains in these glycoproteins has also been hypothesized. |
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