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Molecular docking analysis of phytocompounds from Andrographis paniculata binding with proteins in the notch-signaling pathway |
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| Authors: | Sumetha Suga Deiva Suga Surapaneni Krishna Mohan Radhika Nalinakumari Sreekandan Malathi K Devakumar Kamaraj Vishnu Priya Veeraraghavan Selvaraj Jayaraman Ponnulakshmi Rajagopal |
| Abstract: | It is of interest to document the molecular docking analysis of phytocompounds from Andrographis paniculata binding with protein NOTCH1 in the Notch-signaling pathway in the context of cancer. Hence, we document the binding features of neoandrographolide, 14-deoxyandrographolide, androgapholide and andrograpanin with proteins in the notch-signaling pathway for further consideration. |
| Keywords: | Gastric Cancer Notch signaling pathway Andrographis paniculata Molecular docking studies |